Mobility Studies

About Mobility Studies:

Mobility Studies indicate a test substance’s potential for adsorption to soil, sediments and sludge.Therefore, mobility studies estimate a test substance’s movement in the natural environment.  Such data is used to determine what environmental compartment the test substance will migrate to and its possibility to contaminate ground water.  Mobility tests are conducted by Smithers Viscient using EPA and OECD Test Guidelines for Adsorption/Desorption and Soil Column Leaching.    

Adsorption/Desorption Testing:

Smither Viscient offers Adsorption/Desorption testing in soils, sediment and activated sludge.  Soil may originate from the US, Europe, South America and Asia.  Studies can be designed to meet specific client needs. Preliminary tests are conducted to ensure the test substance does not bind to the test vessel sand that the test substance is stable during equilibrium and through the time course of the study. Endpoints include %sorption, Kd, Kdes and Koc.  Additional endpoints such as Kom and also Freudlich Isotherm Constants, KF can also be determined depending on the level of testing. 

 

Soil Column Leaching Studies (and Aged Soil Column Leaching):

Soil column leaching testing measures the distance a test substance travels down a water-saturated soil column.  The test is generally conducted with a reference substance that has a known migration potential and adsorption coefficient so an RMF (relative mobility factor) can be calculated and reported. Smither Viscient conducts this test according to OECD and EPA Test Guidelines with soils from US, Europe and other continents from around the world.  This test can be adapted to EU guidance on refining the adsorption coefficients of test substances with very low Koc values.  Additional aged column leaching test can be designed with a pre-incubation period of up to 30 days in soil prior to applying the treated soil to the soil column in order to obtain the leaching potential of the test substance and its metabolites.

 

Equipment and Instrumentation includes:

  • Temperature controlled chambers
  • Shaker tables
  • LSC counters
  • Agilent, Shimadzu, Waters HPLC systems
  • Metabolite characterization and identification instrumentation: Sciex 4000 QTRAP® and accurate mass Sciex Triple TOF 5600 Q® mass spectrometers